ʻO ka hoʻolaha ʻana o ka hydrogen ma o nā metala ma nā mahana kiʻekiʻe he kumuhana koʻikoʻi ia no nā ʻōnaehana tritium a me nā kaʻa i hoʻohana ʻia e ka hydrogen. ʻO ke aʻo ʻana i ka hoʻolaha ʻana ma ka hale hana mea lae pua e pōmaikaʻi mai ka ʻike lima mua me nā ana osmotic. Ua hoʻonohonoho ʻia kahi hoʻokolohua e hōʻike i ke komo ʻana o ka hydrogen ma o kahi paipu kila kila. ʻO ke kumu o kēia hana, ʻo ia ka hoʻoholo ʻana i ka maikaʻi o nā hopena o kēia hoʻokolohua e kūlike me nā waiwai palapala koʻikoʻi no ka coefficient diffusion a me ka solubility o ka hydrogen i loko o ke kila kila. Ua hui pū ʻia ka hydrogen a me ka argon i loko o kahi pahu wela e loaʻa ana kahi paipu kila kila 316. Ua hoʻouna ʻia ke kinoea purge argon maʻemaʻe ma o ka paipu i loko o kahi spectrometer mass kahi i hoʻopaʻa ʻia ai nā transients compositional o nā ʻano kinoea like ʻole. ʻO ke kau ʻana i ke kumu hoʻohālike hoʻololi theoretical i ka ʻikepili hoʻokolohua i loaʻa ka coefficient diffusion a me ka solubility o ka hydrogen i loko o ke kila kila. Ua hana ʻia nā hoʻokolohua ma ke kaomi hana o ka hydrogen mai 0.01 a 0.5 atm. a me nā mahana mai 700 a 783 K. Kūpono ke kumu hoʻohālike theoretical i ke ʻano o ka ʻikepili penetration transient. Ua like nā waiwai i ʻike ʻia no ka hoʻolaha ʻana a me ka solubility o ka hydrogen i loko o ke kila kila mai kēia mau transients me nā waiwai palapala me kekahi mau ʻokoʻa. Hiki ke wehewehe ʻia kēia mau ʻokoʻa e nā hanana i ʻike ʻia. Ua kokoke loa nā hopena o kēia ʻano hoʻokolohua i nā waiwai diffusion a me solubility i paʻi ʻia, kahi e hōʻoiaʻiʻo ai e hiki ke hoʻohana ʻia ka hoʻokolohua ma ke ʻano he kōkua aʻo. Hiki ke hoʻonui ʻia ke ʻano i nā mea ʻē aʻe no nā kumu noiʻi a hōʻike paha.
Ua hoʻomohala ʻia ka papahana SUU Nursing i loko o ke kahua kumumanaʻo kumu o ka hoʻonaʻauao i kau ʻia ma ka haumāna. Ua komo maikaʻi nā haumāna i ke kaʻina hana aʻo, akā ma ke ʻano he hui, ʻaʻole hiki iā lākou ke loaʻa ka ʻike pilikino e pono ai e holomua ma NCLEX. Lawe nā haumāna i nā papa hana hānai me ka ʻole o ka lawe ʻana i ke kuleana no ka ʻike ʻoiaʻiʻo. ʻAʻole lawa nā hana aʻo hui e hōʻike i ka ʻike o nā haumāna pākahi. ʻO ka nānā ʻana i ka hemahema o nā haumāna ma o ka hoʻāʻo maʻamau e paipai i ke Kula o ka Nursing e ʻimi i nā loli i ke aʻo ʻana. ʻO nā mea nui o ke kumumanaʻo hoʻomohala constructivist e hāʻawi i ka ʻike i ka loli pedagogical maikaʻi i kūleʻa no kā mākou mau haumāna puka. Hōʻike kēia hōʻike i nā ʻano i ka ʻikepili mai nā hoʻokolohua maʻamau i hoʻohana ʻia i loko o ka papahana mālama a me nā hopena NCLEX. Hāʻawi kēia hōʻike i ke kākoʻo no ka hana e hoʻolaha i nā manaʻo o ke kumumanaʻo hoʻomohala constructivist a me kā lākou noi i ka hoʻonaʻauao hānai. He nui nā hiʻohiʻona kumumanaʻo o ka hoʻonaʻauao hānai e hoʻāʻo nei e kau i ke kahua no ka papa hana hānai. ʻO nā hoʻoponopono aʻo ma ka ʻOihana Nursing o SUU e kūlike me ke kumumanaʻo hoʻomohala constructivist, a kākoʻo mau nā hopena aʻo haumāna i kēia manaʻo.
ʻO Daphne Solomon, DNP, FNP-C Diane Fuller*, DNP, APRN, FNP-C, Debra Whipple*, DNP, FNP-BC, Ana Sanchez-Birkhead, PhD, WHNP-BC Ke Keʻena Hana Hānai
ʻO ka maʻi ʻaʻai umauma mumū (IBCC) ka ʻano maʻi ʻaʻai umauma ʻoi loa ka ʻino a me ka make. He maʻi make honua ka IBC i ka wā ma mua, akā i kēia lā, ʻo ke ola ʻana o 5 makahiki he 30-40% (Bond, Connoly, & Asci, 2010). He maʻi make honua ka IBC i ka wā ma mua, akā i kēia lā, ʻo ka nui o ke ola ʻana he 5 makahiki he 30-40% (Bond, Connoly, & Asci, 2010). Когда-то ИБК был смертельно опасным заболеванием, но сегодня 5-летняя выживаемость составляет (,Bond,10,0%). He maʻi make ʻo IB i ka wā ma mua, akā i kēia lā ʻo ka nui o ke ola ʻana he 5 makahiki he 30-40% (Bond, Connoly, & Asci, 2010). Когда-то ИБК был смертельно опасным заболеванием, но сегодня 5-летняя выживаемость составляет (&1 Bosci, 20%). He maʻi make ʻo IB i ka wā ma mua, akā i kēia lā ʻo ka nui o ke ola ʻana he 5 makahiki he 30-40% (Bond, Connoly & Asci, 2010).ʻO IBC ka helu no 1% a 6% o nā maʻi āpau i loaʻa i ka maʻi umauma. He mea kupanaha i ke kauka a me ka mea maʻi ka laha ʻole (Molckovsky et al., 2009). ʻIke mua ka hapa nui o nā maʻi i kā lākou kauka mālama mua (PCP). Hoʻomaopopo hewa pinepine ʻia ʻo IBC he cellulitis umauma a mastitis paha. Ua paʻi ʻia ka hapa nui o nā palapala e pili ana iā IB ma nā puke pai oncology. ʻIke pinepine ʻole ʻia ma nā puke pai mālama mua, gynecology, a i ʻole nā ​​​​​​puka puke lapaʻau kūloko. Ua hōʻike kahi loiloi o nā puke aʻo ma ka lāʻau lapaʻau a me ka pathophysiology i ka ʻike liʻiliʻi i loaʻa i nā haumāna lapaʻau. ʻO ka pahuhopu o kēia papahana ka hoʻomaikaʻi ʻana i ka ʻike o nā mea maʻi a me nā mea lawelawe mālama ola i nā hōʻailona, ​​​​nā hōʻailona, ​​​​nā pae hōʻailona, ​​​​a me nā alakaʻi e pili ana me IBC.
ʻO ke Kumu Hoʻohālike Manaʻoʻiʻo Ola (HBM) ke kumu kumumanaʻo no kēia papahana. Ma o ka hoʻonaʻauao ʻana i nā mea maʻi PCP a me IBC, hiki i ka ʻike mua ʻana a me ka hōʻoia ʻana i kēia maʻi ke alakaʻi i kahi prognosis maikaʻi aʻe.
ʻO Alyssa Simon Beveridge, ʻo Madison Rae, ʻo Jessica Brown, ʻo Emily Clendening, ʻo Sierra Gish, ʻo Nika Clark*, ʻo Cynthia Wright, Ph.D.* Keʻena ʻOihana ʻEpekema Mahiʻai a me ka Meaʻai
Ua hōʻike nā Centers for Disease Control and Prevention he 35.9% o nā mākua o ʻAmelika Hui Pū ʻIa he momona, 8.9% he pre-diabetic, a he 8.3% ka maʻi diabetes.
ʻO ka pahuhopu o ka papahana, ʻo ia ke hoʻoholo inā he pilina ma waena o ka momona o ke kino a me ke kō koko kiʻekiʻe a me nā mea ʻē aʻe e pili ana i ke olakino ma waena o nā haumāna, nā kumu, a me nā limahana ma ke kahua kula o ke Kulanui o Southern Utah. Ua lawe ʻia kahi laʻana kūpono o 384 mai ka heluna kanaka o ke kulanui. Ua hoʻopau nā mea komo i kahi noiʻi i ʻāpono ʻia e ka IRB a loaʻa iā lākou ʻekolu mau ana: ke anapuni o ka pūhaka, ka momona o ke kino, a me A1c (he hōʻailona o ka pilikia o ka loaʻa ʻana o ka maʻi diabetes).
Kokoke i ka 5 pakeneka o ka poʻe i komo he kaumaha haʻahaʻa, 26 pakeneka he kaumaha nui, a he 14 pakeneka he momona. Ua hōʻike nā hopena e pili ana i ka pakeneka momona o ke kino i ka piʻi ʻana o ka pakeneka momona o ke kino, pēlā nō hoʻi nā pae A1c, ke anapuni o ka pūhaka, a me ka makahiki. Loaʻa i nā mea i komo male kahi pakeneka momona o ke kino kiʻekiʻe aʻe.
Ma kahi o 6% o ka poʻe i komo he A1c ma luna o 7 (i manaʻo ʻia he kiʻekiʻe). Hoʻopili ʻia ka A1c kiʻekiʻe me ke kūlana male a me ka ʻoluʻolu ʻole i ke kaumaha a me ke olakino kino.
ʻO ka hoʻohana ʻana i nā mea polymeric i ka hana ʻana o nā microchips e ʻoi aku ka pono a me ka maikaʻi o ke aʻo ʻana i ka hoʻokaʻawale microfluidic. Hana mākou i nā microchips i kūkulu ʻia mai nā substrates poly(dimethylsiloxane) (PDMS) me ka hoʻohana ʻana i nā template nickel electrodeposited e hana i nā kahawai hoʻokaʻawale. Ua hoʻomaʻemaʻe ʻia nā substrates PDMS me ka lipine a hōʻike ʻia i ka mālamalama UV i ka hoʻāʻo ʻana e hoʻomaʻemaʻe plasma i ka polymer. Ma hope o ka hoʻomaʻemaʻe ʻana, ua hoʻohui ʻia ʻo PDMS i ka slide aniani e hana i ka lalo o ke kahawai hoʻokaʻawale. ʻO ke ʻano wehe o kēia mau mea microfluidic e ʻae i ka nānā ʻana o nā protein a me nā mole liʻiliʻi me ka hoʻohana ʻana i nā ʻano electrochemical a me spectroscopic.
Ke aʻo nei mākou i ke ʻano o nā lipid phosphatidylserine (PS) i ke alo o ke keleawe. Aia ka PS i loko o nā membrane cell o ka hapa nui o nā meaola a pili i nā kaʻina hana cellular koʻikoʻi a like ʻole e like me ka apoptosis, coagulation, a me ka hoʻoili ʻana o nā maʻi. Ua hōʻike nā haʻawina mua e hoʻopaʻa nā ion keleawe (II) i ka PS a ua hōʻike ʻia e hiki i nā complexes keleawe-PS ke "hoʻohuli" i ka bilayer transmembrane. Ua hoʻohana mākou i ka electrophoresis a me nā microfluidics a ke hoʻohana nei i kahi hopena keleawe-catalyzed e hoʻāʻo e hōʻike inā hana maoli ka inversion o ka complex.
ʻO nā hui organik me nā waiwai antibiotic ke kihi o ka lāʻau lapaʻau a me ke olakino kanaka. Ke manaʻo nei kēia noiʻi e ʻimi i nā ala hou e synthesize i nā antibiotics mai nā mea hoʻomaka maʻalahi. No ka hoʻokō ʻana i kēia pahuhopu, ua hoʻohana ʻia nā hopena cycloaddition photocatalytic [2+2] o nā alkenes a me nā isocyanates i ka mālamalama ʻike ʻia e hoʻomākaukau i nā antibiotics monocyclic lactam. Ua kālele ka hana mua i ka hoʻomohala ʻana i nā kūlana no ka hana hana ma waena o phenylisocyanate a me transstilbene. Ua kālele nā ​​​​hoʻokolohua hou aku i ka hoʻonui ʻana i ka reactivity o ka photocatalyst ma ka hoʻohui ʻana i kahi nui stoichiometric o kahi oxidative quencher. I ka wā e kālailai ai i nā hui hopena e loaʻa ana nā mea hoʻohui oxidizing, ua ʻike ʻia kekahi mau huahana hou. Ke hana nei mākou i kēia manawa i ka hoʻokaʻawale ʻana a me ke ʻano o kēia mau huahana hou.
He salamander ʻo Taricha granulosa e hūnā ana i ka neurotoxin tetrodotoxin (TTX) mai kona ʻili. Hoʻohana nā Salamanders i ka tetrodotoxin ma ke ʻano he pale kūʻē i nā mea ʻaihue. Ua hōʻike ʻia nā pākeke, nā larvae a me nā embryos o Taricha torosa e loaʻa ana iā lākou ka TTX. Makemake mākou e helu i ka nui o ka TTX i hoʻokahe ʻia e nā salamanders ma nā pae like ʻole o ko lākou ola, me nā embryos, larvae (ma mua a ma hope o ka ʻike ʻia ʻana o nā wāwae hope), a me nā salamanders makua. E hoʻohana mākou i ka gas chromatography i hui pū ʻia me ka mass spectrometry (GCMS) a me ka capillary zone electrophoresis (CZE) me ka ʻike ʻana o ka fluorescence microarray e hoʻoholo ai i ka nui o ka TTX. ʻO ka pahuhopu o kā mākou noiʻi ʻana, ʻo ia ke hōʻoia i ka capillary zone electrophoresis he kahua kūpono no ka helu ʻana o ka tetrodotoxin. ʻO ka hoʻohana ʻana o kēia noiʻi, ʻo ia ka loaʻa ʻana o nā pae kumu o ka tetrodotoxin e kōkua i ka noiʻi hou aku.
Ma ke aʻo ʻana i ka hopena Fischer-Indole i ʻike nui ʻia a wehewehe pono ʻia, ua ʻike ʻia nā ala ʻē aʻe no ka hana ʻana o ka indole a me ka carbazole. Pili kēia hopena i manaʻo ʻia i ka hoʻokumu ʻana o nā mea waena like me ke kaʻina hana Fischer. Inā holomua kēia hui ʻana me kahi mea waena maʻamau e like me ka mea i manaʻo ʻia, pono e hāʻawi ka hopena i manaʻo ʻia i ka huahana like me ke kaʻina hana Fischer. Inā ʻoiaʻiʻo kēia, e ʻike ʻia kahi hopena kemika hou.
ʻO ka hopena i manaʻo ʻia no ka synthesis o nā indoles (a me nā carbazoles hope loa) e pili ana i ka hoʻopili ʻana o nā hui nitroso aromatic i nā ʻāpana amine cyclic i loko o kahi ala mechanistic hou. Hōʻike ka papahana ma lalo nei i ka hopena hou i manaʻo ʻia. E hōʻike ʻia ka maʻalahi o kēia hopena i ka pono no nā ʻanuʻu liʻiliʻi a emi ke kumukūʻai a emi ka maʻalahi o ka lawelawe ʻana i nā reagents ma mua o nā ʻano hana synthetic ʻē aʻe. ʻO ka pōmaikaʻi nui loa, ʻaʻole pono ka hydrazine ʻawaʻawa loa e pono ai e hoʻohana i ke ʻano Fisher.
Ua noiʻi ʻia ka hopena ma lalo o nā kūlana hopena like ʻole, me nā mea hoʻoheheʻe like ʻole, nā ʻano pH like ʻole, nā ʻano hana microwave a me nā ʻano hana maʻamau, a me ka hoʻohana ʻana i nā mea hoʻoulu like ʻole.
Ua aʻo ʻia kēia pane, akā ʻaʻole i kūleʻa. ʻAʻole i hoʻokumu ʻia ke kumu o kēia. Pono ka noiʻi hou aku e hoʻoholo i ke kumu i kūleʻa ʻole ai kēia pane a hiki i kēia manawa a pehea e hiki ai ke hoʻohana pono ʻia kēia ʻike.
ʻO RJ Corry, ʻo Taylor Everett, ʻo Cody Hilton, ʻo Bruce Smalley, a me Chris Monson, Ph.D. *Keʻena o nā ʻEpekema Kino
He kuleana koʻikoʻi ko nā membrane cell a me ko lākou mau protein i ke ola o kēlā me kēia lā a he mea hoihoi loa ia i ka poʻe e aʻo ana i ke ola. Ke nānā nui nei ka nui o nā haʻawina i ke kuleana o kēia mau protein a me nā membrane a me kā lākou pilina ma ka noiʻi lāʻau lapaʻau a me ke kumumanaʻo. ʻO ka mea hou loa, ua hoʻohana ʻia nā bilayers lipid i kākoʻo ʻia (SLBs) e hoʻomaʻemaʻe i nā protein membrane me ka hoʻohana ʻana i kahi ʻenehana i kapa ʻia ʻo electrophoresis/electroosmotic focusing (EEF). ʻOiai ua maopopo maikaʻi kēia ʻano hana i ka hoʻomaka a me ka hopena o ka hoʻokaʻawale ʻana o ka lipid/protein, ʻaʻole maopopo loa ke ʻano o kēia mau lipids/proteins ma waena. Ke hoʻāʻo nei mākou e hana i kahi simulation kamepiula e hiki ai iā mākou ke hoʻohālike i ke ʻano o nā lipids a me nā protein i nā pae āpau o ka hoʻokaʻawale ʻana. Ua manaʻo ʻia kēia e kōkua i ka hoʻomaopopo ʻana i nā pilina protein-lipid no ka noiʻi e hiki mai ana.
He papa koʻikoʻi nā imine o nā hui organik e loaʻa ana nā hui hana (CH=N)). Ua kapa ʻia hoʻi lākou he mau kumu Schiff, ma hope o ke kanaka nunui ʻo Schiff nāna i hana iā lākou i ka makahiki 1864. Hana ʻia lākou e nā hopena condensation ma waena o nā aldehydes a i ʻole ketones a me nā amines. Hōʻike ka nui o nā imine i ka hana olaola koʻikoʻi e like me ka antibacterial, antiviral, a me ka hana anticancer. ʻO kā mākou pahuhopu ka hana ʻana o nā imines hou ma o ka hana ʻana o nā N-heterocyclic aldehydes a me nā amines. Hiki i kēia mau imines ke hana ma ke ʻano he ligands bidentate a hana i nā ʻano apo ʻelima-membered paʻa me nā metala hoʻololi. ʻO kekahi pahuhopu o kā mākou papahana ka hoʻopili ʻana o nā imines hou me nā metala d8 (ʻo ia hoʻi ka nickel, platinum a me ka palladium). Manaʻolana mākou e lilo ka complex platinum i hana ʻia i analogue o ka lāʻau antitumor cisplatin. Ma hope o ka hana kūleʻa ʻana, e hoʻāʻo ʻia nā complexes metala no kēia hana olaola hiki.
Ua hana mākou i nā imine hou o 5-aminouracil a me ʻekolu mau N-heterocyclic aldehydes like ʻole. Hōʻike ka ʻikepili 1H-NMR a me IR ua hana mākou i ka imine i makemake ʻia. Ke hoʻomau nei ka hana ma ka hoʻokaʻawale ʻana i nā huahana maʻemaʻe a me ka hana ʻana o kā lākou mau metala paʻakikī. ʻO kahi waiwai pono o kā mākou imine i hana hou ʻia, ʻo ia ko lākou fluoresce ikaika ʻana i ka ʻāpana polū o ka mālamalama ʻike ʻia.
He papa koʻikoʻi nā Alkylamines (RNH2) o nā molekala organik, me nā huahana kūlohelohe biologically a me nā lāʻau lapaʻau. Loaʻa lākou i nā hui koʻikoʻi he nui e like me ka morphine, dopamine a me nā protein āpau. No laila, he mea koʻikoʻi ka hana ʻana o nā alkylamines no ka synthesis o nā lāʻau lapaʻau hou a ʻoi aku ka maikaʻi. Hoʻolaʻa ʻia kēia hana i ka hoʻohana ʻana i nā intermediates alkylborane no ka hoʻokumu ʻana i nā pilina nitrogen-carbon o alkylamines. Ua ʻike nui ʻia ka hydroboration o nā alkenes me ka borane (BH3) a ukali ʻia e ka oxidation me ka hydrogen peroxide (H2O2). Manaʻo mākou i ka hoʻohana ʻana i kēia intermediate alkylborane a ukali ʻia e ka hoʻohana ʻana i nā nitrogen equivalents o ka hydrogen peroxide e hāʻawi i ke komo ʻana i nā alkylamines mai nā alkenes. Ua like ke koho ʻana o ka pūnaewele anti-Markovnikov me ka hydroboroxidation. Ua hoʻokō pono ʻia ka hopena kaohi oxidation e ka hydroboration ma transstilbene. Ke hoʻomohala ʻia nei nā kūlana hoʻokolohua huahua no nā hopena i makemake ʻia.
Hiki ke hoʻohana ʻia nā hopena i hoʻoulu ʻia e nā metala hoʻololi i ka synthesis organik o nā lāʻau lapaʻau, nā mea (plastics), a me nā wahie. ʻO ke ʻano a me nā mea uila o nā ligands phosphine i hoʻonohonoho ʻia i nā kikowaena metala hoʻololi hiki ke hoʻopilikia nui i ka reactivity o nā catalysts. Hoʻolaʻa ʻia kēia noiʻi i ka synthesis o nā ligands phosphine hou no nā hopena hou i hoʻoulu ʻia e nā metala hoʻololi. Ua synthesized ʻia a pale ʻia ka ligand trialkylphosphine reactive kiʻekiʻe diethyl tert-butylphosphine ma ke ʻano he borane adduct mai ka phosphorus trichloride a me nā reagents Grignard e pili ana i ka huina o 66% (4 mau ʻanuʻu). Ua ʻike ʻia he hopena koʻikoʻi nā hopena steric a me nā uila o nā reagents Grignard i ka reactivity a me ke koho ʻana o ka hopena ʻekolu-ʻanuʻu o ka hoʻohui nucleophilic i nā kikowaena phosphorus (III). E kālele ana ka hana e hiki mai ana i ka hoʻomohala ʻana i kahi kaʻina hana maʻamau no ka hoʻomākaukau ʻana o nā trialkylphosphine borane adducts i makemake ʻia mai ka phosphorus trichloride i nā hua kiʻekiʻe.
Ke hoʻomohala nei mākou i kahi ʻano hana hou no ka hana ʻana i nā mea microfluidic me ka hoʻohana ʻana i nā uea metala e like me nā template. Hoʻohana pinepine ʻia nā mea microfluidic i nā hoʻokolohua lapaʻau a me nā hoʻokolohua maʻamau ʻē aʻe, akā ʻo nā kumukūʻai prototyping kiʻekiʻe e kaupalena ana i kā lākou hoʻohana ʻana i nā wahi i emi iki ka versatile e like me ke kemika organik. Hoʻohana kā mākou ʻano hana i nā mea makepono ʻole (uea Mg, PDMS a me HCl) e hoʻohālike a kūkulu i nā mea microfluidic. Ke hoʻāʻo nei mākou i ke ʻano o kā mākou mea microfluidic a ke manaʻolana nei e hoʻomaka i ka hoʻāʻo ʻana i nā hopena organik a me ka hoʻomohala ʻana i nā hiʻohiʻona hou me kā mākou mea microfluidic koke.
ʻO Jacob Anderson, Russell Grimshaw, Adam Hendrickson, Allen Hamekki, Jeremy Leonard lāua ʻo Roger Greener * Ke Keʻena ʻenekinia ʻenehana a me ka hoʻokele kūkulu hale
Ua nui loa ke kumukūʻai o ke kūʻai ʻana a me ka hoʻohana ʻana i nā mīkini paʻi 3D mai ka wā i hoʻomohala mua ʻia ai. Ua nui nā hoʻomaikaʻi ʻana i ke kahua o nā mīkini paʻi 3D i nā makahiki i hala iho nei, e hopena ana i nā kumukūʻai kūʻai haʻahaʻa. Hoʻokumu pū ia i nā ʻano hoʻolālā like ʻole. ʻIke mākou i ka ulu ʻana o ke kahua o nā mīkini paʻi 3D ma ke ʻano he manawa kūpono e ʻimi ai i nā papahana e hoʻomau nei a kūkulu i nā mīkini paʻi 3D no mākou iho. ʻAʻole wale ke kumukūʻai kūpono o kēia mīkini paʻi 3D, akā hoʻohui pū kekahi i nā hoʻolālā maikaʻi loa me nā mea a mākou i hana ai iā mākou iho.
Ke ulu nei ka ʻoihana paikikala mauna i kēlā me kēia makahiki a me kēia ulu ʻana, pono nā ʻenehana hou. Aia nā paikikala mauna iho i ke alo o ka hana hou i ka ikaika o nā mea, nā ʻāpana māmā, ke ʻano o ka mōlina a me ka hana hoʻokuʻu.
Ua hoʻomaka māua ʻo Scott Hansen e hoʻomohala i kahi ʻōnaehana paikikala mauna iho hou me ka hoʻokuʻu maikaʻi loa a me ka lawelawe ʻana. Hoʻohana ka hoʻolālā i kahi ʻōnaehana pushrod maʻalahi e hoʻohuli i kahi pālua o nā cams e hoʻokele i ka hoʻokuʻu hope i ka neʻe ʻana o ka huila hope i luna a i lalo i 8 ʻīniha o ka huakaʻi. ʻAe kēia hoʻolālā lima i ka hoʻokuʻu hope e kau ʻia ma lalo loa i loko o ka ʻōnaehana, e hopena ana i kahi kikowaena haʻahaʻa loa o ke kaumaha a me ka lawelawe maikaʻi loa. Ke pau ka hoʻolālā, e hoʻomaka mākou e kūkulu i kahi ʻōnaehana prototype me nā paipu chrome. Ke mākaukau ka ʻōnaehana, e hōʻuluʻulu ʻia ke paikikala mai nā ʻāpana alumini māmā a me ke kalapona i hāʻawi ʻia a kūʻai ʻia paha. ʻO ka pahuhopu hope loa ka hana ʻana i kahi paikikala mauna iho paʻa, māmā, a hana piha e like me nā mea i heihei ʻia ma ke kaapuni UCI Downhill World Cup.
ʻO Caitlin Torgersen, ʻo Erin Carter, ʻo Cynthia Wright, Ph.D.* a me Nika Clark* Ke Keʻena ʻEpekema Mahiʻai a me ka Meaʻai
ʻO ka metabolic syndrome ka wehewehe ʻana i kahi hui o nā mea pilikia e hoʻonui ai i ka pilikia o ka maʻi cardiovascular, ka maʻi diabetes type 2, a i ʻole ka hahau. ʻO kēia mau mea pilikia e komo pū me ke koko kiʻekiʻe, ke kō koko hoʻokē ʻai kiʻekiʻe, ka piʻi ʻana o ka puni pūhaka, a me nā pae cholesterol maʻamau. Hana ʻia ka metabolic syndrome ke loaʻa ʻekolu a ʻoi aku paha o kēia mau kūlana i ka manawa like. Wahi a ka American Heart Association, 35% o nā pākeke ʻAmelika i loaʻa ka metabolic syndrome (Association, 2011). Ua loiloi kēia haʻawina i nā kumu aʻo a me nā hoa kāne o ke Kulanui o Southern Utah (SUU) no ke alo a i ʻole ka pilikia o ka hoʻomohala ʻana i ka metabolic syndrome (me ʻekolu mau mea pilikia) a i ʻole ka pilikia o ka hoʻomohala ʻana i ka metabolic syndrome (me ʻelua mau mea pilikia). Ma ka hui pū ʻana me ka papahana olakino SUU T-fit, ua hoʻāʻo ʻia he 189 mau mea komo. ʻOi aku ma mua o 33% o nā mea komo i loaʻa ka metabolic syndrome, a ʻo kekahi 21.7% i pilikia no ka hoʻomohala ʻana i ka metabolic syndrome, e like me ka hōʻike ʻana o ke alo o ʻelua mau mea pilikia. Eia kekahi, ua hana ʻia kahi noiʻi e loiloi i nā mea nohona e hiki ke kōkua i ka hoʻomohala ʻana o ka metabolic syndrome. Ua hoʻohana ʻia ʻo SPSS 21.0 e kālailai i ka ʻikepili e hōʻike ana he nui nā mea nohona e hoʻonui ai i ka pilikia o ka hoʻomohala ʻana i ka metabolic syndrome.
ʻO Kaylie Briggs, ʻo Samantha Hirschi, ʻo Sarah Miller, ʻo Kylie Stringham, ʻo Artis Grady, Ph.D.*, ʻo Matthew Schmidt, Ph.D.* Ke Keʻena ʻEpekema Mahiʻai a me ka Meaʻai
ʻO ka ʻai ʻana i ka nui o ka momona i ka ʻai a ka ʻAmelika maʻamau he pilikia mau ia i ke kaiāulu meaʻai. Ma ka hōʻemi ʻana i ka ʻai momona holoʻokoʻa, ʻo ka hoʻomohala holomua ʻana o nā ʻai haʻahaʻa momona hiki ke hana ʻia e ka heluna kanaka maʻamau he mau hopena koʻikoʻi no ka hakakā ʻana i nā maʻi cardiovascular a me ka momona. Ua hoʻokolohua nā mea noiʻi me nā mea hoʻohui maʻamau like ʻole (ʻāpala puree, yogurt, bean puree, a me nā mea ʻē aʻe) i hoʻohana ʻia ma ke ʻano he pani momona e hana i ʻehā mau huahana mea ʻono momona haʻahaʻa i nā meaʻai kaulana. 56-73% ka liʻiliʻi o ka momona ma mua o ke ʻano hana mua. He kanalimakumamāono mau mea komo manawaleʻa, mai 18 a 31 mau makahiki, 37 mau wahine a me 19 mau kāne, i hoʻāʻo i kēlā me kēia mea ʻono a hana i kahi loiloi pōkole o ka huahana. ʻO ka awelika o nā helu ʻae ʻia o ka meaʻai ma kahi pālākiō 7-point (mai 1 makemake ʻole loa a i 7 makemake nui loa) he 4.83 (keke), 5.20 (kuki oatmeal), 5.45 (muffins spiced), a me 5.49 (kuki kokoleka). kuki). Ma hope o ka haʻi ʻia ʻana ua haʻahaʻa ka momona o nā meaʻai, ʻo ka pakeneka o nā mea komo i ʻike i ka ʻae ʻia o nā meaʻai: nā kuki ʻāpana kokoleka (96%), nā kuki oatmeal (93%), nā muffins ʻala (75%), a me nā brownies (64%). ). I ka wā i nīnau ʻia ai nā mea komo e pili ana i nā meaʻai maʻamau e hiki ke pani i ka momona i nā mea i hoʻomoʻa ʻia, ʻaʻohe ʻike o nā mea komo. Ua ʻike pololei lākou i ka hiki ke hoʻohana ʻia ka applesauce a me ka yogurt, akā ua kuhi hewa lākou i nā pani kō, ka waiū, ka margarine, ka palaoa palaoa piha, a me ke kō ʻeleʻele. ʻOiai ua loaʻa i kēia heluna kanaka nā meaʻai haʻahaʻa momona i hoʻāʻo ʻia, hiki iā lākou ke pōmaikaʻi mai ke aʻo ʻana e pili ana i nā pani momona kūpono a pehea e hoʻohana ai iā lākou i nā meaʻai ma ke ʻano he hoʻolālā e hōʻemi ai i ka lawe ʻana i ka momona i ka meaʻai.
ʻO Eric Carter, ʻo Aubrey Lyman, ʻo Robert Miguel, ʻo Ryland Morrill, ʻo Kashaana Renfro, ʻo Dallen Whitney, a me Cynthia Wright, Ph.D.* Keʻena ʻOihana ʻEpekema Mahiʻai a me ka Meaʻai
He maʻi maʻamau ka Osteoporosis kahi e loaʻa ai nā haki iwi he nui. ʻO ka hapa nui o ia mea e loaʻa ai ma ka iwi kuamoʻo, ka ʻūhā, a i ʻole ka pulima lima a hiki ke hopena i ka ʻeha nui a i ʻole ka make. Ua manaʻo ʻia ka nui o ka osteoporosis ma ʻAmelika Hui Pū ʻIa e piʻi aʻe mai kahi 10 miliona a ʻoi aku ma mua o 14 miliona ma ka makahiki 2012 (ma muli o ka ʻikepili Census 2000). Me ke kiʻekiʻe o ka nui o ka iwi i ka wā ʻōpiopio, emi iho ka pilikia o ka osteoporosis. ʻO ka komo ʻana i ka hana kino, e like me nā haʻuki i hoʻonohonoho ʻia, e pili pinepine ʻia me ka piʻi ʻana o ka nui o ka iwi.
Ua noiʻi ka papahana noiʻi i nā nīnau aʻe: Ke loli nei ka nui o ka iwi o ke kanaka me ke komo ʻana i ka hana kino?
Ua ʻike ʻia kēia haʻawina i kahi pilina maikaʻi ma waena o ka hana kino o ke ola a me ka nui o nā mineral iwi, e hōʻike ana he ʻoi aku ka nui o ka iwi o ka poʻe i hana kino i ko lākou ola a pau ma mua o ka poʻe i loaʻa nā pae hana haʻahaʻa o ke ola. . ʻOi aku ka nui o ka poʻe i hana ʻole i ke kino i ka haʻahaʻa o ka iwi (ma kahi o 10% o ko mākou heluna kanaka) ma mua o ka poʻe me nā pae hana haʻahaʻa, waena a kiʻekiʻe. Ua hōʻike ʻia nā haʻawina i ka piʻi ʻana o nā pae hana, piʻi ka likelika o ka iwi maʻamau a kiʻekiʻe paha.
ʻO Kauka Portia Terry, ʻo Megan Beasley lāua ʻo Cynthia Wright* Keʻena ʻEpekema Mahiʻai a me ka Meaʻai
Ma ʻAmelika Hui Pū ʻIa, 35.7% o nā pākeke he kaumaha a momona paha (cdc.gov). Manaʻo ʻia he nui nā kumu e kōkua ana i kēia maʻi ahulau, e like me ka loaʻa ʻana o ka meaʻai a me ka nui o nā ʻāpana. Ua loiloi kēia haʻawina i ka hopena o nā hana hoʻonaʻauao meaʻai i ka ʻike meaʻai a me ke ʻano ʻai. Ma kēia haʻawina, ua noi ʻia nā haumāna i kākau inoa ʻia i kahi papa meaʻai maʻamau e hoʻopau i kahi noiʻi ma mua a ma hope e pili ana i ka ʻike e pili ana i ke ʻano ʻai a me nā nui o nā ʻāpana. Ma hope o ka hoʻāʻo mua, ua hāʻawi nā mea noiʻi i nā haumāna i ka ʻike e pili ana i nā nui o nā ʻāpana. ʻEkolu pule ma hope mai, ua hāʻawi ʻia nā haumāna i kahi hoʻāʻo ma hope e loiloi i nā loli. ʻO nā mea komo ʻē aʻe he mau kumu a me nā hoa kāne i komo i ka loiloi olakino o ke Kulanui o Southern Utah. Hoʻopau nā kumu a me kā lākou mau hoa kāne i hoʻokahi wale nō noiʻi a ʻaʻole i loaʻa i kekahi ʻike hoʻonaʻauao. Ma ka huina, he 260 mau haumāna a me 190 mau limahana/kumu/hoa kāne i komo i ka noiʻi. Ua kālailai ʻia ka ʻikepili me ka hoʻohana ʻana i ka paʻi 21 o ka Statistical Package for the Social Sciences. Ua hana ʻia nā hoʻāʻo-t i hui pū ʻia ma nā hoʻāʻo mua a me hope o nā haumāna, a ua hoʻohana ʻia nā hoʻāʻo-t kūʻokoʻa e hoʻohālikelike i nā pane a nā haumāna i nā limahana/kumu/kāne/kāne/wahine. Manaʻo ʻia nā hopena.
ʻO Kauka Fabiola Perez, Joshua Sagisi, Emanuel Williams, Jan-Andro Hakob a me Cindy Wright * Keʻena ʻOihana Mahiʻai a me nā Meaʻai.
ʻO ka hōʻike ʻana i ke alo o ka bacteria E. coli i loko o kēlā me kēia hāpana wai e hiki ai iā ʻoe ke nānā i ka maikaʻi o ka wai ʻōmole a me ka wai paipa. ʻO nā Coliforms nā meaola hōʻailona mai ka kumu bacteria like e ʻike ana i ke alo o nā pathogens he nui. ʻAʻole ʻōlelo ʻia e nānā i nā microorganism ʻē aʻe no ke alo o nā pathogens weliweli ʻē aʻe ma muli o ko lākou wahi like ʻole. (Byamukama lāua ʻo Kanshiime et al., 1999). Hiki iā E. coli ke ola i ka wai inu no 4 a 12 mau pule ma muli o nā kūlana o ke kaiapuni (Rice, Karlin, Allen, 2012). E hoʻāʻo ʻia he ʻumi mau lama wai ʻōmole like ʻole no ka bacteria E. coli, a me ka wai paipa mai nā hale like ʻole he ʻumi. Hōʻike ʻia kēlā me kēia lama wai ʻōmole a me ka wai paipa no ka hoʻohana ʻana i ka home ma ke ʻano ʻekolu. I ka manawa like, ua kau ʻia ka nui o nā hāpana wai i loko o ka incubator no ka nānā ʻana a me ka hoʻoulu ʻana i ka ulu ʻana o ka bacteria. E hoʻoholo kēia i ka maʻemaʻe o kēlā me kēia hāpana. E kau ʻia nā hāpana i loko o kahi lumi pouli kahi e hoʻohana ʻia ai ke kukui UV e hoʻomālamalama i nā hāpana e ʻike i ke alo o E. coli. (Rice, Carlin, Allen, 2012).
Ua ʻeli nui ʻia nā Mauna ʻo Kapalakiko ma ke komohana hema o Utah i nā makahiki he ʻumi i hala iho nei. Hoʻopili nui ʻia ka hana ʻeli ʻana ma nā monzonites quartz Tertiary, nā pōhaku limestone Paleozoic intrusive. Loaʻa nā kumuwaiwai koʻikoʻi ma nā ʻaoʻao o ʻelua mau hewa nui i waiwai i nā waihona porphyry hydrothermal, akā ʻaʻole i hoʻopaʻa pono ʻia ke kihi o kēia mau hewa ma muli o ka ʻino o ka pōhaku. Ma ka hana pū ʻana me kahi hui ʻeli kūloko, ua hoʻomaka nā haumāna o Southern Utah i ka palapala ʻāina mua e ʻimi a wehewehe i kēia keʻa hewa ma mua o ka hoʻomau ʻana me ka ʻimi ʻana. Ua palapala ʻāina mākou i kahi o nā haki i hōʻike ʻia me ka hoʻohana ʻana i kahi mea hana GPS Triton Juno a ua ana i ko lākou density a me ke kuhikuhi ʻana o ka haki me ka hoʻohana ʻana i ke kaulike Brenton a me ka compass. Hōʻike nā hopena o nā kiʻikuhi rose, stereograms a me nā palapala ʻāina i ke alo o nā intersections i loko o ka wahi aʻo. Hoʻonui ka nui o ka haki i ka wā e hoʻokokoke ʻia ai nā intersections, ʻoi aku hoʻi ma kekahi o nā kuhikuhi haki, a maʻamau ka mineralization kūloko ma nā hewa. Paipai mākou i ka ʻimi hou ʻana ma ke ʻano o ka ʻeli ʻana i ke kumu ma nā intersections hewa mineralized e hoʻoholo ai i ka hiki ke hoʻohana waiwai.
Ua ʻimi ʻia nā mauna ʻo Huahua kokoke iā Minasville, Utah, no nā minelala no nā makahiki he ʻumi i hala iho nei. Hoʻopili ʻia nā kumuwaiwai i nā hewa porphyritic i hoʻololi ʻia e ka hydrothermally, ma ke ʻano maʻamau kahi i komo ai nā monzonites quartz tertiary i loko o nā pōhaku limestone Paleozoic. Ma waho aʻe o ka magmatism Tertiary, hōʻike nā mauna ʻo Huahua i kahi paʻi koʻikoʻi o ka orogeny Late Cretaceous o Seville, e kau ana i nā pōhaku sedimentary Paleozoic ma luna o nā pōhaku sedimentary Middle Cretaceous. I ka wā o kahi papahana palapala ʻāina kūkulu ma ia wahi, ua ʻike ʻia ua hana ʻia ka silicification hydrothermal o ka one o Navajo ma ka wāwae o ka Blue Mountains Thrust, e like me ka quartzite. Ma hope o ka nānā pono ʻana, ua ʻike ʻia nā mineralizations hydrothermal ʻē aʻe. Hoʻololi kēia mau hopena i ka nānā ʻana i ka noiʻi mai ka palapala ʻana i ka geology kūkulu i ka palapala ʻana i nā hoʻololi hydrothermal kūikawā i nā one one Navajo.
Aia i loko o kēia haʻawina nā ʻano hana aʻe. Ma ka ʻāpana o nā Mauna Polū, ke hana ʻia nei kahi ʻimi no nā waihona kokoke i ka ikaika o ka wā Sevier. Ua hōʻiliʻili ʻia nā laʻana o ka one pōhaku Jurassic Navajo a ua hana ʻia nā ʻāpana lahilahi e kālailai i ka ʻike metala o ka pōhaku. Loaʻa i nā laʻana i loaʻa kokoke i ka wēlau hikina loa o ka Blue Mountains Thrust Fault ka quartz, hematite, a me nā metala liʻiliʻi ʻē aʻe. ʻAʻole waiwai nui ka mineralization, akā me ka hohonu e hoʻonui ana, hiki ke nui aʻe nā waihona o nā metala i loko o nā aa. Pono ka loiloi hou aʻe, e like me ka nānā ʻana i ka umekaumaha a me ka ʻikepili kumu, e hoʻoholo i ka waiwai o ka mineralization.
ʻO Spencer Francisco, ʻo John S. McLean, Ph.D.*, a me Michael Hofmann, Ph.D.*, Keʻena o nā ʻEpekema Kino
ʻO nā Pōhaku Puke ma ka hikina hema o Utah ke kahua pāʻani no nā hanauna o nā geologists sedimentary clastic. Ua aʻo nui ʻia ka nui o nā puka i waho no ka mea he mau hoa maikaʻi lākou no kekahi mau waihona wai inshore, offshore a terrestrial. Eia nō naʻe, ʻo ka hapa nui o nā puka i waho e hāʻawi wale i nā kiʻi 2D a ʻaʻole hiki ke wehewehe piha i ke ʻano stratigraphic a me ka heterogeneity facies. Ma kēia haʻawina, hōʻike mākou i ka ʻikepili mai nā cores outcrop hou mai ka Upper Cretaceous Price Canyon, Castlegate a me Blackhawk Formations. ʻO ke aʻo ʻana, he ʻāpana o ka hui pū ʻana ma waena o ke Kulanui o Southern Utah a me ke Kulanui o Montana, i kālele ʻia i ke ʻano o ke ʻano 3D subsurface a me ka heterogeneity facies o kēia mau ʻano mai kahi moʻo o nā cores. Aia nā cores i wehewehe ʻia ma ʻaneʻi i kahi nui o nā facies sedimentary e pili ana me nā hoʻonohonoho kahakai a me ke kahakai. Loaʻa i nā pōhaku e pili ana me nā wahi Blackhawk Formation nā ʻāpana koʻikoʻi o ka one keʻokeʻo, fine-grained, modded a cross-modded me nā laminations silt maikaʻi i hoʻokaʻawale ʻia e nā pōhaku lepo wili a me nā modded hina a ʻeleʻele, nā pōhaku silt hina, a me nā seams o ka lanahu.
Hoʻākāka mākou i kēia mau ʻeke e like me ke ʻano o ka hoʻololi ʻana mai kahi ʻano planar kahakai/deltaic i hoʻomalu ʻia e nā kaʻina hana fluvial i kahi ʻano fluvial piha i ka wā Castlegate. ʻOkoʻa ka mānoanoa o ke kino one (ka nui o ke kahawai) me ka manawa, me nā kahawai multilayer e hui pinepine ana i ka wā Castlegate. E hoʻomau ʻia ka noiʻi, e hoʻomaka ana me kahi loiloi ʻōnaehana o nā cores i koe a hoʻopau me kahi moʻo o nā papahana haumāna ma ka loiloi facies a me ke kumu hoʻohālike 3D facies.
Ua hāpai mua nā mea noiʻi i kahi ʻano hana no nā tectonics ʻelua-papa ma Mars e pili ana i ka neʻe ʻana o ka hoʻololi hema o ke awāwa ʻo Mariner. Ma ka hoʻohana ʻana i nā ʻano hana e like me ke kiʻi satelite Thermal Imaging System (THEMIS), nā kiʻi satelite High Resolution Science Imaging Experiment (HiRISE), nā hiʻohiʻona kiʻekiʻe kikohoʻe, a me nā polokalamu hana like e like me Google Mars, ua ʻike mākou i nā hiʻohiʻona ʻili nui kokoke i ke awāwa ʻo Marineris. . a me Tarsis Ryze. ʻOiai ʻoi aku ka lohi o ka neʻe ʻana o ka tectonic ma Mars, hiki iā mākou ke hoʻohālikelike i nā laina, nā pelu, a me nā hui conjugate o Mars me nā ʻano like ma ka Honua e wehewehe i nā palena papa hiki. No ka laʻana, hiki i kahi hoʻonohonoho o nā laina trend NE me ka neʻe ʻana o ka strike-slip lateral koʻikoʻi a me nā hui pili ma ka ʻākau hikina o ka Tarshish Rise ke hoʻokipa i nā neʻe ʻana ma waena o ʻelua mau papa. Hiki i kā mākou mau nānā ʻana ke ʻike i ʻelua mau lihi hou aʻe o nā papa hiki ma kēia ʻāina. Hāʻawi mākou i kahi kumu hoʻohālike tectonic e hōʻike ana i ka neʻe pili ma nā palena papa e hōʻike ana i kahi ʻōnaehana multi-plate ma Mars.
Ma ke ʻano hoʻokaʻawale ʻana o ke aniau ʻo Köppen, ua wehewehe ʻia ke aniau maloʻo/semi-arid a i ʻole ke aniau B he aniau kahi e ʻoi aku ai ka mahu ma mua o ka ua. Eia naʻe, ʻaʻole ʻo ia i hāʻawi i kahi kaʻina hana helu kūhelu. Ke hāpai nei mākou i kahi inoa hou, ʻo ka potential excess precipitation (PEP), ma ke ʻano he ala kūpono no ka wehewehe ʻana i nā wahi semi-arid a me nā wahi humid. Ua like ka waiwai PEP me ka nui maoli o ka ua me ka ʻole o ka potential evapotranspiration (POTET). Inā maikaʻi ka waiwai PEP, ʻo ke aniau o ke kikowaena ʻo A, C, a i ʻole D, akā inā maikaʻi ʻole ka waiwai PEP, ʻo ke aniau o ke kikowaena ʻo B. ʻO ka hoʻopili ʻana i ka waiwai PEP e hāʻawi i kēlā me kēia kikowaena i kahi waiwai maikaʻi a maikaʻi ʻole paha e hiki ke hoʻolālā ʻia, a wehewehe ka contour null i kahi palena semi-dry-wet.
ʻO ke kahua ʻo Kaiparowitz, aia ma ke kikowaena hema o Utah, ka mea nona ka moʻolelo no ke kahawai wai o ka Late Cretaceous i kahe mai nā ʻĀina Kiʻekiʻe ʻo La Ramedia a i ke Ala Wai o Western Inland. Nui nā fossil i loko o ke kahua a loaʻa nā mea kanu fossil, nā invertebrates, nā iʻa, nā amphibians, nā reptiles a me nā mammals, he nui o ia mau mea he mea hou i ka ʻepekema. Ua wehewehe mua ʻia nā wehewehe nui o kēia kahua he mau waihona wai a me nā kahawai wai e loaʻa ana nā waihona swamp a me nā loko like ʻole. Hāʻawi kēia haʻawina i kahi wehewehe sedimentological kikoʻī o kahi lua pōhaku mea kanu liʻiliʻi a wehewehe i nā kūlana waiho ʻana.