ʻO ka laha ʻana o ka hydrogen ma o nā metala i nā wela kiʻekiʻe he kumuhana koʻikoʻi no nā ʻōnaehana tritium a me nā kaʻa hydrogen.ʻO ke aʻo ʻana i ka laha ʻana i loko o nā haʻawina haʻahaʻa haʻahaʻa haʻahaʻa e pōmaikaʻi mai ka ʻike mua me nā ana osmotic.Ua hoʻonohonoho ʻia kahi hoʻokolohua e hōʻike i ke komo ʻana o ka hydrogen ma o ka paipu kila kuhili.ʻO ke kumu o kēia hana ʻo ia ka hoʻoholo ʻana i ka ʻae ʻana o nā hopena o kēia hoʻokolohua me nā waiwai palapala koʻikoʻi no ka diffusion coefficient a me ka solubility o ka hydrogen i ke kila kila.Ua hui pū ʻia ka hydrogen a me ka argon i loko o kahi pahu mehana i loaʻa i kahi paipu kila kila 316.Ua hoʻoili ʻia ke kinoea hoʻomaʻemaʻe argon maʻemaʻe ma o ka paipu i loko o kahi spectrometer nui kahi i hoʻopaʻa ʻia ai nā transients haku mele o kēlā me kēia ʻano kinoea.ʻO ka hoʻokomo ʻana i ke ʻano hoʻololi manaʻo i ka ʻikepili hoʻokolohua i loaʻa ai ka diffusion coefficient a me ka solubility o ka hydrogen i loko o ke kila kila.Ua lawe ʻia nā hoʻokolohua ma kahi kaomi hana o ka hydrogen mai 0.01 a i 0.5 atm.a me nā mahana mai 700 a i 783 K. Ua kūpono ke kumu hoʻohālike i ke ʻano o ka ʻikepili transient penetration.ʻO nā waiwai i ʻike ʻia no ka diffusion a me ka solubility o ka hydrogen i ke kila kila mai kēia mau transients ua like ia me nā waiwai palapala me kekahi mau ʻokoʻa.Hiki ke wehewehe ʻia kēia mau ʻokoʻa e nā hanana i ʻike ʻia.Ua kokoke loa nā hopena o kēia ʻano hoʻokolohua i nā waiwai diffusion a me solubility i paʻi ʻia, e hōʻoiaʻiʻo ana e hiki ke hoʻohana ʻia ka hoʻokolohua ma ke ʻano he kōkua aʻo.Hiki ke hoʻonui ʻia ke ʻano i nā mea ʻē aʻe no ka noiʻi a i ʻole ka hana hōʻikeʻike.
Ua hoʻomohala ʻia ka papahana kahu hānai SUU i loko o ke kumu kumu kumu o ka hoʻonaʻauao i hoʻokumu ʻia i nā haumāna.Ua komo maikaʻi nā haumāna i ke kaʻina aʻo, akā ma ke ʻano he hui ʻaʻole hiki iā lākou ke loaʻa ka ʻike pilikino ponoʻī e pono ai ke kūleʻa ma NCLEX.Lawe nā haumāna i nā papa kahu hānai me ka lawe ʻole i ke kuleana no ka ʻike maoli.ʻAʻole lawa nā hana aʻo pūʻulu e hōʻike i ka ʻike o kēlā me kēia haumāna.ʻO ke kālailai ʻana i ka haʻahaʻa o ka haumāna ma o ka hoʻāʻo maʻamau e paipai i ke kula kahu hānai e ʻimi i nā loli o ke aʻo ʻana.ʻO nā mea nui o ka manaʻo hoʻomohala constructivist e hāʻawi i ka ʻike i ka hoʻololi aʻoaʻo maikaʻi i kūleʻa i kā mākou mau haumāna puka.Hōʻike kēia hōʻike i nā ʻano o ka ʻikepili mai nā hoʻokolohua maʻamau i hoʻohana ʻia i loko o ka papahana mālama a me nā hopena NCLEX.Hāʻawi kēia hōʻike i ke kākoʻo no ka hana e holomua i nā manaʻo o ke kumumanaʻo constructivist developmental a me kā lākou noi i ka hoʻonaʻauao kahu.Nui nā kumu hoʻohālike o ka hoʻonaʻauao kahu hānai e hoʻāʻo e kau i ke kumu no ka papa hana kahu.Kūlike nā hoʻololi aʻo ʻana ma ke Keʻena kahu hānai o SUU me ka manaʻo hoʻomohala constructivist, a kākoʻo mau nā hopena aʻo haumāna i kēia manaʻo.
Daphne Solomon, DNP, FNP-C Diane Fuller*, DNP, APRN, FNP-C, Debra Whipple*, DNP, FNP-BC, Ana Sanchez-Birkhead, PhD, WHNP-BC Keʻena kahu hānai
ʻO ka maʻi ʻaʻai umauma inflammatory (IBCC) ʻo ia ke ʻano koʻikoʻi a make loa o ka maʻi maʻi umauma. ʻO ka IBC he maʻi maʻi maʻi āpau, akā i kēia lā ʻo 5-makahiki ke ola ʻo 30-40% (Bond, Connoly, & Asci, 2010). ʻO ka IBC he maʻi maʻi maʻi āpau, akā i kēia lā ʻo 5 mau makahiki ola ola he 30-40% (Bond, Connoly, & Asci, 2010). Когда-то ИБК был смертельно опасным заболеванием, но сегодня 5-летняя выживаемость составляет (,Bond,10,0%). He maʻi make ʻo IB i kekahi manawa, akā i kēia lā ʻo 30-40% ka nui o ke ola 5 makahiki (Bond, Connoly, & Asci, 2010). Когда-то ИБК был смертельно опасным заболеванием, но сегодня 5-летняя выживаемость составляет (&1 Bosci, 20%). He maʻi make ʻo IB i kekahi manawa, akā i kēia lā ʻo 30-40% ka nui o ke ola o 5 mau makahiki (Bond, Connoly & Asci, 2010).ʻO ka IBC ka helu no 1% a 6% o nā maʻi maʻi āpau āpau.He malihini ka Rarity i ke kauka a me ka mea maʻi (Molckovsky et al., 2009).ʻIke mua ka hapa nui o nā maʻi i kā lākou kauka mālama mua (PCP).Hoʻomaopopo pinepine ʻia ʻo IBC e like me ka cellulitis umauma a i ʻole mastitis.Ua paʻi ʻia ka hapa nui o nā puke e pili ana i ka IB ma nā nūpepa oncology.ʻAʻole ʻike ʻia ma ka mālama mua, gynecology, a i ʻole nā ​​puke lāʻau lapaʻau kūloko.Ua hōʻike ʻia kahi loiloi o nā puke ma ka lāʻau lapaʻau a me ka pathophysiology i nā ʻike liʻiliʻi i loaʻa i nā haumāna lapaʻau.ʻO ka pahuhopu o kēia papahana ʻo ia ka hoʻomaikaʻi ʻana i ka ʻike e nā poʻe maʻi a me nā mea mālama olakino i nā hōʻailona, ​​​​nā hōʻailona, ​​​​nā kumu diagnostic, a me nā alakaʻi e pili ana me IBC.
ʻO ka Health Belief Model (HBM) ke kumu kumu no kēia papahana.Ma o ka hoʻonaʻauao maʻi PCP a me IBC, hiki i ka ʻike mua ʻana a me ka hōʻoia ʻana o kēia maʻi ke alakaʻi i kahi wānana maikaʻi aʻe.
ʻO Alyssa Simon Beveridge, Madison Rae, Jessica Brown, Emily Clendening, Sierra Gish, Nika Clark*, Cynthia Wright, Ph.D.* Keʻena ʻOihana Mahiai a me nā Meaʻai.
Ke hōʻike nei nā Centers for Disease Control and Prevention he 35.9% o ka poʻe mākua US he obese, 8.9% he pre-diabetic, a he 8.3% ka maʻi maʻi.
ʻO ka pahuhopu o ka papahana ʻo ia ka hoʻoholo inā loaʻa kahi hui ma waena o ka momona o ke kino a me ke kō koko kiʻekiʻe a me nā ʻano hoʻololi ʻē aʻe e pili ana i ke olakino ma waena o nā haumāna, kumu, a me nā limahana ma ke kahua o ke Kulanui o Southern Utah.Ua kiʻi ʻia kahi laʻana maʻalahi o 384 mai ka heluna o ke kulanui.Ua hoʻopau ka poʻe i komo i kahi noiʻi i ʻae ʻia e IRB a loaʻa iā lākou ʻekolu ana: ka ʻapo o ka pūhaka, ka momona o ke kino, a me ka A1c (he hōʻailona o ka pilikia o ka ulu ʻana i ka maʻi diabetes).
Ma kahi kokoke i 5 pakeneka o ka poʻe i komo ma lalo o ke kaumaha, 26 ka nui o ke kaumaha, a he 14 ka nui o ka momona.Ua hōʻike ʻia nā hualoaʻa e pili ana i ka pākēneka momona o ke kino i ka piʻi ʻana o ka pākēneka o ka momona o ke kino, ua piʻi aʻe nā pae A1c, ka ʻapo o ka pūhaka, a me ka makahiki.Ua ʻoi aku ka nui o ka momona o ke kino i ka poʻe i male.
Ma kahi kokoke i 6% o nā mea komo i loaʻa ka A1c ma luna o 7 (manaʻo ʻia he kiʻekiʻe).Hoʻopili ʻia ka A1c kiʻekiʻe me ke kūlana male a me ka ʻoluʻolu ʻole i ke kaumaha a me ke olakino kino.
ʻO ka hoʻohanaʻana i nā mea polymeric i ka hanaʻana i nā microchips eʻoi aku ka maikaʻi a me ka maikaʻi o ke aʻoʻana i ka hoʻokaʻawale microfluidic.Hana mākou i nā microchips i kūkulu ʻia mai ka poly(dimethylsiloxane) (PDMS) substrates me ka hoʻohana ʻana i nā template nickel electrodeposited e hana i nā ala kaʻawale.Hoʻomaʻemaʻe ʻia nā substrates PDMS me ka lipine a ʻike ʻia i ke kukui UV i ka hoʻāʻo ʻana e hoʻomaʻemaʻe plasma i ka polymer.Ma hope o ka hoʻomaʻemaʻe ʻana, ua hoʻohui ʻia ʻo PDMS i ka paheʻe aniani e hana i lalo o ke kahawai hoʻokaʻawale.ʻO ke ʻano hāmama o kēia mau mea microfluidic e ʻae i ka nānā ʻana i nā protein a me nā molekole liʻiliʻi me ka hoʻohana ʻana i nā ʻenehana electrochemical a spectroscopic.
Ke aʻo nei mākou i ka hana o ka phosphatidylserine (PS) lipids i mua o ke keleawe.Aia ʻo PS i loko o nā membrane cell o ka hapa nui o nā mea ola a ua komo i nā kaʻina cellular koʻikoʻi a like ʻole e like me ka apoptosis, coagulation, a me ka lawe ʻana i nā maʻi.Ua hōʻike ʻia nā haʻawina mua e hoʻopaʻa ʻia nā ion keleawe (II) i ka PS a ua hōʻike ʻia e hiki i nā paʻakikī keleawe-PS ke "hoʻohuli" i ka transmembrane bilayer.Ua hoʻohana mākou i nā electrophoresis a me nā microfluidics a ke hoʻohana nei mākou i ka hopena copper-catalyzed e hoʻāʻo e hōʻike inā hiki maoli ka hoʻohuli ʻana o ka paʻakikī.
ʻO nā pūhui organik me nā waiwai antibiotic ka pōhaku kihi o ka lāʻau lapaʻau a me ke olakino kanaka.Ke manaʻo nei kēia noiʻi e ʻimi i nā ala hou e synthesize i nā antibiotic mai nā mea hoʻomaka maʻalahi.No ka hoʻokō ʻana i kēia pahuhopu, ua hoʻohana ʻia nā hopena cycloaddition photocatalytic [2+2] o nā alkenes a me nā isocyanates i ka mālamalama ʻike ʻia no ka hoʻomākaukau ʻana i nā antibiotic monocyclic lactam.Hoʻokumu ka hana mua i ka hoʻomohala ʻana i nā kūlana no ka hopena hana ma waena o phenylisocyanate a me transstilbene.ʻO nā hoʻokolohua hou aʻe i kālele ʻia i ka hoʻonui ʻana i ka reactivity o ka photocatalyst ma o ka hoʻohui ʻana i ka nui stoichiometric o kahi mea hoʻopau oxidative.I ka nānā ʻana i nā hui ʻana i loaʻa nā mea hoʻohui oxidizing, ua ʻike ʻia kekahi mau huahana hou.Ke hana nei mākou i ka hoʻokaʻawale ʻana a me ke ʻano o kēia mau huahana hou.
ʻO Taricha granulosa kahi salamander e hūnā i ka neurotoxin tetrodotoxin (TTX) mai kona ʻili.Hoʻohana nā Salamanders i ka tetrodotoxin ma ke ʻano he pale i nā mea ʻaihue.Ua hōʻike ʻia i nā pākeke, nā larvae a me nā embryos o Taricha torosa i loaʻa iā TTX.Makemake mākou e helu i ka nui o ka TTX i hoʻokahe ʻia e nā salamanders ma nā ʻano like ʻole o ko lākou ola, me nā embryos, larvae (ma mua a ma hope o ke ʻano o nā wāwae hope), a me nā salamanders makua.E hoʻohana mākou i ka chromatography kinoea i hui pū ʻia me ka mass spectrometry (GCMS) a me ka capillary zone electrophoresis (CZE) me ka ʻike fluorescence microarray e hoʻoholo ai i ka manaʻo TTX.ʻO ka pahuhopu o kā mākou noiʻi ʻana ʻo ia ka hōʻoia ʻana i ka electrophoresis capillary zone kahi kahua kūpono no ka helu ʻana o ka tetrodotoxin.ʻO ka noi o kēia haʻawina ʻo ia ka loaʻa ʻana o nā pae kumu o ka tetrodotoxin e kōkua i ka noiʻi hou aku.
Ma ke aʻo ʻana i ka hopena Fischer-Indole kaulana a maikaʻi hoʻi, ua ʻike ʻia nā ala ʻē aʻe no ka synthesis o indole a me ka carbazole.ʻO kēia pane i manaʻo ʻia e pili ana i ka hoʻokumu ʻana i nā mea waena like me ke kaʻina hana Fischer.Inā hoʻomaka kēia hui ʻana me kahi waena waena e like me ka mea i manaʻo ʻia, pono e hāʻawi ka hopena i manaʻo ʻia e like me ke kaʻina hana Fischer.Inā ʻoiaʻiʻo kēia, e ʻike ʻia kahi hopena kemika hou.
ʻO ka pane i manaʻo ʻia no ka hoʻohui ʻana o nā indoles (a ʻo ka hope loa o nā carbazoles) pili i ka hui ʻana o nā pūhui nitroso ʻala i nā ʻāpana amine cyclic ma kahi ala mechanistic novel.Hōʻike ka papahana ma lalo nei i ka pane hou i manaʻo ʻia.E hōʻike ʻia ka ʻoluʻolu o kēia pane i ka pono o nā ʻanuʻu liʻiliʻi a me ka liʻiliʻi o ke kumukūʻai a me ka maʻalahi o ka mālama ʻana i nā reagents ma mua o nā ʻano hana synthetic.ʻO ka pōmaikaʻi nui loa, ʻaʻole koi ʻia ka hydrazine ʻona nui e hoʻohana ai i ke ʻano Fisher.
Ua noiʻi ʻia ka hopena ma lalo o nā ʻano hopena like ʻole, me nā solvents like ʻole, nā ʻano pH like ʻole, ka microwave a me nā ʻano hana maʻamau, a me ka hoʻohana ʻana i nā catalysts like ʻole.
Ua aʻo ʻia kēia pane, akā naʻe, ʻaʻole i kūleʻa.ʻAʻole i hoʻokumu ʻia ke kumu o kēia.Pono e noiʻi hou aʻe no ka hoʻoholo ʻana i ke kumu i kūleʻa ʻole ai kēia pane a pehea e hoʻohana pono ʻia ai kēia ʻike.
RJ Corry, Taylor Everett, Cody Hilton, Bruce Smalley, a me Chris Monson, Ph.D.* Keʻena ʻepekema kino
He kuleana koʻikoʻi nā membrane cell a me kā lākou mau protein i ke ola o kēlā me kēia lā a makemake nui i ka poʻe e aʻo i ke ola.Ke hoʻonui nei ka nui o nā haʻawina e pili ana i ka hana o kēia mau protein a me nā membrane a me kā lākou mau pilina ma ka noiʻi lāʻau lapaʻau a me ka theoretical.I kēia mau lā, ua hoʻohana ʻia nā lipid bilayers (SLBs) i kākoʻo ʻia e hoʻomaʻemaʻe i nā protein membrane me ka hoʻohana ʻana i kahi ʻenehana i kapa ʻia ʻo electrophoresis/electroosmotic focusing (EEF).ʻOiai ua hoʻomaopopo maikaʻi ʻia kēia ʻano hana ma ka hoʻomaka a me ka hopena o ka hoʻokaʻawale ʻana o ka lipid/protein, ʻaʻole maopopo ka ʻano o kēia mau lipids/proteins i waena.Ke hoʻāʻo nei mākou e hana i kahi simulation kamepiula e hiki ai iā mākou ke hoʻohālikelike i ka ʻano o nā lipids a me nā protein i nā pae āpau o ka kaʻawale.Manaʻo ʻia kēia e kōkua i ka hoʻomaopopo ʻana i ka pilina protein-lipid no ka noiʻi e hiki mai ana.
He papa koʻikoʻi nā Imines o nā pūhui organik i loaʻa (CH=N)) pūʻulu hana.Ua kapa ʻia lākou he kumu Schiff, ma hope o ka Schiff nunui nāna i hoʻohui iā lākou i ka makahiki 1864. Hoʻohui ʻia lākou e nā hopena condensation ma waena o nā aldehydes a i ʻole nā ​​​​ketones a me nā amines.Hōʻike ka nui o nā imine i ka hana olaola koʻikoʻi e like me ka hana antibacterial, antiviral, a me ka hana anticancer.ʻO kā mākou pahuhopu, ʻo ia ka synthesis o nā imine hou e ka hopena o N-heterocyclic aldehydes a me nā amines.Hiki i kēia mau imine ke hana ma ke ʻano he bidentate ligands a hana i nā hale apo lima paʻa me nā metala hoʻololi.ʻO kekahi pahuhopu o kā mākou papahana ʻo ia ka paʻakikī o nā imine hou me nā metala d8 (ʻo ia hoʻi ka nickel, platinum a me ka palladium).Manaʻo mākou e lilo ka paʻakikī platinum synthesized i mea hoʻohālikelike o ka lāʻau antitumor cisplatin.Ma hope o ka hoʻohui maikaʻi ʻana, e hoʻāʻo ʻia nā paʻakikī metala no kēia hana olaola.
Ua hana mākou i nā imine hou o 5-aminouracil a me ʻekolu mau N-heterocyclic aldehydes.Hōʻike ka ʻikepili 1H-NMR a me IR ua hoʻohui mākou i ka imine i makemake ʻia.Ke hoʻomau nei ka hana i ka hoʻokaʻawale ʻana i nā huahana maʻemaʻe a me ka synthesis o kā lākou mau mea metala.ʻO kahi waiwai maikaʻi o kā mākou imine hou i hoʻohui ʻia, ʻo ia ka mea e lele ikaika ana i ka ʻāpana polū o ka mālamalama ʻike ʻia.
ʻO Alkylamines (RNH2) kahi papa koʻikoʻi o nā molekala organik, me nā huahana kūlohelohe kūlohelohe a me nā lāʻau lapaʻau.Loaʻa iā lākou i loko o nā pūhui koʻikoʻi he nui e like me morphine, dopamine a me nā protein āpau.No laila, he mea koʻikoʻi ka hana ʻana o nā alkylamines no ka synthesis o nā lāʻau hou a ʻoi aku ka maikaʻi.Hana ʻia kēia hana i ka hoʻohana ʻana i nā alkylborane intermediates no ka hoʻokumu ʻana i nā paʻa nitrogen-carbon o nā alkylamines.ʻIke maikaʻi ʻia ka hydroboration o nā alkenes me ka borane (BH3) a ukali ʻia e ka oxidation me ka hydrogen peroxide (H2O2).Manaʻo mākou i ka hoʻohana ʻana i kēia alkylborane intermediate a ukali ʻia e ka hoʻohana ʻana i nā mea like nitrogen o ka hydrogen peroxide e hāʻawi i ke ala i nā alkylamines mai nā alkenes.ʻO ke koho o ka pūnaewele anti-Markovnikov e like me ka hydroboroxidation.Ua hoʻokō maikaʻi ʻia ka hopena o ka oxidation control e ka hydroboration ma ka transstilbene.Ke kūkulu ʻia nei nā kūlana hoʻokolohua huahana no nā hopena i makemake ʻia.
Hiki ke hoʻohana ʻia nā hopena i hoʻopaʻa ʻia e nā metala hoʻololi i ka synthesis organik o nā lāʻau lapaʻau, nā mea (plastic), a me nā wahie.ʻO ke ʻano a me nā mea uila o nā ligand phosphine i hui pū ʻia i nā kikowaena metala hoʻololi hiki ke hoʻopilikia nui i ka reactivity o nā catalysts.Hoʻolaʻa ʻia kēia noiʻi i ka synthesis o nā ligand phosphine hou no nā hopena hou i hoʻopili ʻia e nā metala hoʻololi.ʻO ka trialkylphosphine ligand diethyl tert-butylphosphine ikaika loa i hana ʻia a pale ʻia ma ke ʻano he borane adduct mai ka phosphorus trichloride a me nā mea hoʻohui Grignard e pili ana i ka huina o 66% (4 mau ʻanuʻu).Ua ʻike ʻia he hopena koʻikoʻi ka hopena steric a me ka uila o Grignard reagents i ka reactivity a me ke koho ʻana o ka hopena ʻekolu o ka hoʻohui nucleophilic i nā kikowaena phosphorus (III).E kālele ana ka hana i ka wā e hiki mai ana i ka hoʻomohala ʻana i ke kaʻina hana maʻamau no ka hoʻomākaukau ʻana i ka hoʻohui ʻana o ka trialkylphosphine borane i makemake ʻia mai ka phosphorus trichloride i nā hua kiʻekiʻe.
Ke hoʻomohala nei mākou i kahi ala hou no ka hana ʻana i nā mea microfluidic me ka hoʻohana ʻana i nā uea metala ma ke ʻano he laʻana.Hoʻohana maʻamau nā mea microfluidic i nā hoʻokolohua lapaʻau a me nā hoʻokolohua maʻamau ʻē aʻe, akā palena nā kumukūʻai prototyping kiʻekiʻe i kā lākou hoʻohana ʻana i nā hoʻonohonoho liʻiliʻi e like me ke kemika organik.Hoʻohana kā mākou hana i nā mea kūʻai ʻole (Mg wire, PDMS a me HCl) e hoʻohālike a kūkulu i nā mea microfluidic.Ke hoʻāʻo nei mākou i ke ʻano o kā mākou mea microfluidic a manaʻolana e hoʻomaka i ka hoʻāʻo ʻana i nā hopena kūlohelohe a me ka hoʻomohala ʻana i nā hiʻohiʻona hou me kā mākou mea microfluidic koke.
ʻO Jacob Anderson, ʻo Russell Grimshaw, ʻo Adam Hendrickson, ʻo Allen Hamekki, ʻo Jeremy Leonard a me Roger Greener * Keʻena ʻenehana ʻenehana a me ka hoʻokele kūkulu hale.
Ua pāpā ʻia nā mea paʻi 3D e kūʻai a hana mai ka wā i kūkulu mua ʻia ai.Ua nui ka hoʻomaikaʻi ʻana i ke kahua o nā mea paʻi kiʻi 3D i nā makahiki i hala iho nei, e hopena i nā kumukūʻai kūʻai haʻahaʻa.Hoʻokumu pū ia i nā ʻano hoʻolālā ākea.ʻIke mākou i ka ulu ʻana o nā mea paʻi 3D ma ke ʻano he manawa kūpono e ʻimi ai i nā papahana e holo nei a kūkulu i nā paʻi 3D no mākou iho.ʻAʻole kūʻai wale kēia paʻi 3D, akā hoʻohui pū i nā hoʻolālā maikaʻi loa me nā mea a mākou i hana ai iā mākou iho.
Ke ulu nei ka ʻoihana paikika mauna i kēlā me kēia makahiki a me kēia ulu ʻana, pono nā ʻenehana hou.Aia nā paikika mauna iho i mua o ka hana hou i ka ikaika waiwai, nā ʻāpana māmā, ka geometry frame a me ka hana hoʻomaha.
Ua hoʻomaka māua ʻo Scott Hansen e hoʻomohala i kahi kaʻa kaʻa kaʻa mauna hou me ka hoʻokuʻu ʻana a me ka lawelawe ʻana.Hoʻohana ka hoʻolālā i kahi ʻōnaehana pushrod maʻalahi e hoʻohuli i ʻelua mau kāmela e hoʻokele i ka hoʻokuʻu hope ʻana i ka neʻe ʻana o ka huila hope i luna a i lalo i 8 iniha o ka huakaʻi.Hāʻawi kēia hoʻolālā lima i ka haʻalulu hope e kau ʻia ma kahi haʻahaʻa i loko o ke kiʻi, e hopena i kahi kikowaena haʻahaʻa o ka umekaumaha a me ka lawelawe maikaʻi ʻana.Ke pau ka hoʻolālā ʻana, e hoʻomaka mākou e kūkulu i kahi kiʻi prototype me nā paipu chrome.Ke mākaukau ke kiʻi, e hōʻuluʻulu ʻia ke kaʻa mai nā ʻāpana alumini māmā a kūʻai ʻia mai ke kalapona.ʻO ka pahuhopu hope loa, ʻo ia ka hana ʻana i kaʻa kaʻa mauna mauna paʻa, māmā, hana piha e like me nā heihei ma ke kaapuni ʻo UCI Downhill World Cup.
ʻO Caitlin Torgersen, Erin Carter, Cynthia Wright, Ph.D.* a me Nika Clark* Keʻena ʻOihana Mahiʻai a me nā Meaʻai.
Hōʻike ka Metabolic Syndrome i kahi pūʻulu o nā mea pilikia e hoʻonui ai i ka pilikia o ka maʻi cardiovascular, type 2 diabetes, a i ʻole ka hahau.ʻO kēia mau mea pilikia e pili ana i ke koko kiʻekiʻe, hoʻokiʻekiʻe i ke kō koko hoʻokē ʻai, hoʻonui ʻia ka pōʻai pūhaka, a me nā pae cholesterol maʻamau.Hana ʻia ka Metabolic Syndrome ke loaʻa ʻekolu a ʻoi aku paha o kēia mau kūlana i ka manawa like.Wahi a ka American Heart Association, 35% o nā poʻe ʻAmelika e loaʻa i ka metabolic syndrome (Association, 2011).Ua loiloi kēia haʻawina i nā kumu kula a me nā hoa kāne o ke Kulanui o Southern Utah (SUU) no ka hele ʻana a i ʻole ka pilikia o ka hoʻomohala ʻana i ka metabolic syndrome (me ʻekolu mau mea pilikia) a i ʻole ka pilikia o ka hoʻomohala ʻana i ka metabolic syndrome (me ʻelua mau mea pilikia).Ma ka hui pū ʻana me ka papahana olakino SUU T-fit, ua hoʻāʻo ʻia nā mea komo 189.ʻOi aku ma mua o 33% o nā mea komo i loaʻa i ka metabolic syndrome, a ʻo kekahi 21.7% i ka pilikia no ka hoʻomohala ʻana i ka metabolic syndrome, e like me ka ʻike ʻia e ka loaʻa ʻana o ʻelua mau mea pilikia.Eia kekahi, ua hana ʻia kahi noiʻi e loiloi i nā mea ola e hiki ke kōkua i ka ulu ʻana o ka metabolic syndrome.Ua hoʻohana ʻia ʻo SPSS 21.0 e kālailai i ka ʻikepili e hōʻike ana he nui nā mea ola e hoʻonui ai i ka pilikia o ka hoʻomohala ʻana i ka metabolic syndrome.
ʻO Kaylie Briggs, Samantha Hirschi, Sarah Miller, Kylie Stringham, Artis Grady, Ph.D.*, Matthew Schmidt, Ph.D.* Keʻena ʻOihana Mahiʻai a Meaʻai.
ʻO ka hoʻohana ʻana i ka nui o ka momona i ka meaʻai o ka ʻAmelika maʻamau he pilikia mau ia i ke kaiāulu meaʻai.Ma ka hōʻemi ʻana i ka ʻai momona o ka meaʻai holoʻokoʻa, hiki i ka hoʻomohala kūleʻa ʻana i nā meaʻai momona haʻahaʻa i hiki ke hana ʻia e ka lehulehu ākea he mau hopena koʻikoʻi no ka hakakā ʻana i ka maʻi cardiovascular a me ka momona.Ua hoʻāʻo nā mea noiʻi me nā mea maʻamau like ʻole (apple puree, yogurt, bean puree, a me nā mea ʻē aʻe) i hoʻohana ʻia ma ke ʻano he momona momona no ka hana ʻana i ʻehā mau meaʻai momona haʻahaʻa i nā meaʻai kaulana.56-73% liʻiliʻi ka momona ma mua o ka meaʻai kumu.He kanalimakumamāono i komo manawaleʻa, ʻo 18 a hiki i 31, 37 wahine a me 19 kāne, ʻono i kēlā me kēia mea ʻai a hana i kahi loiloi pōkole o ka huahana.He 4.83 (keke), 5.20 (kuki oatmeal), 5.45 (mau muffins), a me 5.49 (kuki kokoleka).kuki).Ma hope o ka haʻi ʻia ʻana he haʻahaʻa ka momona o nā meaʻai, ʻo nā pākēneka o ka poʻe i komo i ʻike i nā meaʻai e ʻae ʻia: nā kuki kokoleka (96%), nā kuki oatmeal (93%), nā muffins ʻala (75%), a me nā brownies (64%).).I ka wā i nīnauʻia ai nā mea komo e pili ana i nā mea maʻamau e hiki ke pani i ka momona i loko o nā mea i kāluaʻia,ʻaʻoheʻike o nā mea komo.Ua ʻike pololei lākou i ka hiki ke loaʻa i ka ʻāpala a me ka yogurt, akā ua kuhi hewa ʻia nā mea pani kō, ka waiū, ka margarine, ka palaoa palaoa a me ke kō.ʻOiai ua loaʻa i kēia heluna nā meaʻai momona haʻahaʻa i hoʻāʻo ʻia, hiki iā lākou ke pōmaikaʻi mai ke aʻo ʻana e pili ana i nā mea momona momona kūpono a pehea e hoʻohana ai ia mau mea i loko o nā ʻano meaʻai ma ke ʻano he hoʻolālā e hōʻemi i ka ʻai ʻana i ka momona.
ʻO Eric Carter, Aubrey Lyman, Robert Miguel, Ryland Morrill, Kashaana Renfro, Dallen Whitney, a me Cynthia Wright, Ph.D.* Keʻena ʻOihana Mahiʻai a Meaʻai.
ʻO Osteoporosis kahi maʻi maʻamau i loaʻa i nā iwi he nui.Loaʻa pinepine ia ma ka iwi kuamoʻo, ʻūhā, a i ʻole lima lima a hiki ke hopena i ka ʻeha nui a i ʻole ka make.Ua manaʻo ʻia ka piʻi ʻana o ka osteoporosis ma ʻAmelika Hui Pū ʻIa mai kahi o 10 miliona a ma luna o 14 miliona ma 2012 (e pili ana i ka ʻikepili 2000 Census).Me ke kiʻekiʻe o ka iwi iwi i ka wā ʻōpiopio, e emi ana ka pilikia o ka osteoporosis.ʻO ke komo ʻana i ka hana kino, e like me nā haʻuki i hoʻonohonoho ʻia, pili pinepine ʻia me ka piʻi ʻana o ka iwi iwi.
Ua noiʻi ka papahana noiʻi i nā nīnau penei: E loli ana ka iwi iwi o ke kanaka me ka hoʻoikaika kino?
Ua loaʻa i kēia noiʻi kahi pilina maikaʻi ma waena o ka hoʻoikaika kino kino a me ka nui o ka mineral iwi, e hōʻike ana he ʻoi aku ka nui o ka iwi i ko lākou ola kino ma mua o ka poʻe haʻahaʻa haʻahaʻa o ka hana ola..ʻOi aku ka nui o ka iwi haʻahaʻa (ma kahi o 10% o ko mākou heluna kanaka) ma mua o ka poʻe haʻahaʻa, haʻahaʻa a kiʻekiʻe.Ua hōʻike nā haʻawina i ka piʻi ʻana o nā pae hana, piʻi ka nui o ka iwi maʻamau a kiʻekiʻe paha.
ʻO Kauka Portia Terry, Megan Beasley lāua ʻo Cynthia Wright * Keʻena ʻOihana Mahiʻai a me nā ʻEpekema Meaʻai
Ma ʻAmelika Hui Pū ʻIa, ʻo 35.7% o nā poʻe mākua ke kaumaha a paʻakikī paha (cdc.gov).Ua manaʻo ʻia kekahi mau kumu e hāpai i kēia maʻi maʻi, e like me ka loaʻa ʻana o ka meaʻai a me ka nui o nā ʻāpana.Ua nānā kēia haʻawina i ka hopena o nā hana hoʻonaʻauao meaʻai i ka ʻike meaʻai a me ka ʻai ʻana.Ma kēia haʻawina, ua noi ʻia nā haumāna i komo i kahi papa meaʻai maʻamau e hoʻopau i kahi noiʻi ma mua a ma hope o ka ʻike e pili ana i ka ʻai a me ka nui o nā ʻāpana.Ma hope o ka ho'āʻo mua, hāʻawi nā mea noiʻi i nā haumāna i ka ʻike e pili ana i ka nui o nā ʻāpana.ʻEkolu pule ma hope mai, ua hāʻawi ʻia nā haumāna i kahi hoʻokolohua post-test e loiloi i nā loli.ʻO nā mea ʻē aʻe he kumu kula a me nā kāne i komo i ka loiloi olakino o ke Kulanui o Southern Utah.Hoʻokahi wale nō noiʻi i hoʻopau nā kumu a me kā lākou mau hoa kāne a ʻaʻole i loaʻa i nā ʻike hoʻonaʻauao.ʻO ka huina, 260 haumāna a me 190 limahana/kumu/kāne i komo i ka anamanaʻo.Ua kālailai ʻia ka ʻikepili me ka hoʻohana ʻana i ka 21st edition o ka Statistical Package for the Social Sciences.Ua hana ʻia nā hoʻāʻo-t i hui ʻia ma nā hoʻokolohua ma mua a ma hope o nā haumāna, a ua hoʻohana ʻia nā hoʻāʻo t kūʻokoʻa e hoʻohālikelike i nā pane a nā haumāna i nā limahana / kumu / kāne.Manaʻo ʻia nā hopena.
ʻO Kauka Fabiola Perez, Joshua Sagisi, Emanuel Williams, Jan-Andro Hakob a me Cindy Wright * Keʻena ʻOihana Mahiʻai a me nā Meaʻai.
ʻO ka hōʻike ʻana i ka loaʻa ʻana o ka bacteria E. coli i loko o kēlā me kēia laʻana wai e ʻae iā ʻoe e nānā i ka maikaʻi o nā ʻōmole a me ka wai paipu.ʻO Coliforms nā meaola hōʻailona mai ka kumu bacteria like e ʻike ai i ka hiki ʻana mai o nā pathogens.ʻAʻole ʻōlelo ʻia e nānā i nā microorganism ʻē aʻe no ka hele ʻana o nā pathogens ʻē aʻe ma muli o kā lākou localization ʻokoʻa.(Byamukama a me Kanshiime et al., 1999).Hiki i ka E. coli ke ola i loko o ka wai inu no 4 a 12 mau pule ma muli o ke kūlana kaiapuni (Rice, Karlin, Allen, 2012).E hoʻāʻo ʻia nā ʻōmole wai ʻumi he ʻumi no ka bacteria E. coli, a me ka wai paipu mai nā hale ʻokoʻa he ʻumi.Hōʻike ʻia kēlā me kēia hōʻailona o ka ʻōmole wai a me ka wai paipu no ka hoʻohana ʻana i ka home ma ka ʻekolu.I ka manawa like, waiho ʻia ka nui o nā ʻano wai i loko o ka incubator no ka nānā ʻana a me ka hoʻoulu ʻana i ka ulu ʻana o ka bacteria.E hoʻoholo kēia i ka maʻemaʻe o kēlā me kēia hāpana.E waiho ʻia nā laʻana i loko o kahi lumi ʻeleʻele kahi e hoʻohana ʻia ai ke kukui UV e hoʻomālamalama i nā laʻana e ʻike ai i ka hele ʻana o E. coli.(Rice, Carlin, Allen, 2012).
Ua ʻeli nui ʻia nā mauna ʻo Kapalakiko ma ke komohana hema o Utah i nā makahiki i hala.Hoʻopili nui ʻia ka mining ma Tertiary quartz monzonites, intrusive Paleozoic limestones.Loaʻa nā kumuwaiwai koʻikoʻi ma nā hapa nui ʻelua i loaʻa i nā waihona porphyry hydrothermal, akā ʻaʻole i kākau maikaʻi ʻia ka hui ʻana o kēia mau hemahema ma muli o ka pōʻino o ka pōhaku.Ma ka hana pū ʻana me kahi ʻoihana mining kūloko, ua hoʻomaka nā haumāna o Southern Utah i ka palapala palapala mua e ʻimi a hōʻike i kēia hewa ma mua o ka hoʻomaka ʻana i ka ʻimi.Hoʻopili mākou i ka wahi o nā haʻihaʻi i hōʻike ʻia me ka hoʻohana ʻana i kahi hāmeʻa Triton Juno GPS a ana i ko lākou ʻano nui a me ka haʻihaʻi ʻana me ka hoʻohana ʻana i kahi kaulike Brenton a me ke panana.Hōʻike nā hopena o nā kiʻi rose, stereograms a me nā palapala ʻāina i ka loaʻa ʻana o nā kuʻuna i loko o ka wahi aʻo.Piʻi ka nui o ka haʻihaʻi i ka wā e hoʻokokoke ʻia ai nā ʻāpana, ʻoi aku ka nui ma kekahi o nā kuhikuhi haʻihaʻi, a maʻamau ka mineralization kūloko ma nā hemahema.Manaʻo mākou i ka ʻimi hou aku ma ke ʻano o ka wili kumu ma nā ʻāpana hewa mineralized e hoʻoholo ai i ka hiki ke hoʻohana ʻia i ka hoʻokele waiwai.
Ua ʻimi ʻia nā mauna ʻo Huahua kokoke i Minasville, Utah no nā minelala no nā makahiki i hala.Hoʻopili ʻia nā kumuwaiwai i nā hewa porphyritic hydrothermally i hoʻololi ʻia, maʻamau kahi i hoʻokomo ʻia nā monzonites quartz tertiary i loko o nā limestones Paleozoic.Ma waho aʻe o ka Tertiary magmatism, hōʻike nā mauna Huahua i kahi ʻano nui o ka Late Cretaceous orogeny o Seville, e kau ana i nā pōhaku sedimentary Paleozoic ma luna o nā pōhaku sedimentary Cretaceous Middle.I ka wā o kahi papahana palapala palapala ma ia wahi, ua ʻike ʻia ka pōhaku one Navajo ma ka wāwae o ka Blue Mountains Thrust i loaʻa i ka hydrothermal silicification, e like me ka quartzite.Ma ka nānā pono ʻana, ua ʻike ʻia nā mineralization hydrothermal ʻē aʻe.Hoʻololi kēia mau hopena i ka manaʻo noiʻi mai ka palapala ʻana i ke kālaihonua kūkulu ʻana i ka palapala ʻana i nā hoʻololi hydrothermal kūʻokoʻa ma nā pōhaku one Navajo.
Aia kēia haʻawina i nā ʻano hana.Ma kahi o nā Blue Mountains, ke hoʻomaka nei kahi ʻimi no nā waihona kokoke i ke kuʻi o ka wā Sevier.Ua hōʻiliʻili ʻia nā laʻana o ka pōhaku one Jurassic Navajo a ua hana ʻia nā ʻāpana lahilahi e kālailai i ka ʻike metala o ka pōhaku.Loaʻa nā laʻana ma kahi kokoke i ka piko hikina loa o ka Blue Mountains Thrust Fault he quartz, hematite, a me nā metala liʻiliʻi ʻē aʻe.ʻAʻole waiwai nui ka mineralization, akā me ka hoʻonui ʻana i ka hohonu, ʻoi aku ka nui o nā waihona metala i loko o nā veins.ʻO ka nānā hou aku, e like me ka nānā ʻana o ka gravity a me ka ʻikepili kumu, pono e hoʻoholo i ka waiwai o ka mineralization.
Spencer Francisco, John S. McLean, Ph.D.*, a me Michael Hofmann, Ph.D.*, Keʻena ʻEpekema Kino.
ʻO ka Book Rocks ma ka hikina hema ʻo Utah kahi kahua pāʻani no nā hanauna o nā mea kālaihonua sedimentary clastic.Ua aʻo nui ʻia ka nui o nā outcrops no ka mea he mau mea hoʻohālikelike maikaʻi no ka nui o nā loko iʻa, waho a me ka honua.Eia nō naʻe, hāʻawi ka hapa nui o nā outcrops i nā kiʻi 2D wale nō a ʻaʻole hiki ke hōʻike piha i ke ʻano stratigraphic a me ka heterogeneity facies.Ma kēia noiʻi ʻana, hōʻike mākou i nā ʻikepili mai nā core outcrop hou mai ka Upper Cretaceous Price Canyon, Castlegate a me Blackhawk Formations.ʻO ke aʻo ʻana, he ʻāpana o ka hui pū ʻana ma waena o ke Kulanui o Southern Utah a me ke Kulanui o Montana, i kālele ʻia i ka ʻike ʻana i ke ʻano o ka 3D subsurface structure a me ka hoʻohālikelike ʻana i ka heterogeneity o kēia mau hoʻokumu ʻana mai ke ʻano o nā cores.Aia i loko o nā kiko i hō'ike 'ia ma 'ane'i he heluna nui o nā facies sedimentary e pili ana i ka ho'onohonoho kahakai a me ke kahakai.Aia nā pōhaku e pili ana i nā kahua ʻo Blackhawk Formation i nā ʻāpana koʻikoʻi o ke one keʻokeʻo, ʻili maikaʻi, moe a me ke keʻa me nā lamina silika maikaʻi i hoʻokaʻawale ʻia e nā pōhaku ʻeleʻele hina a ʻeleʻele, nā pōhaku ʻeleʻele hina, a me nā hili lanahu.
Wehewehe mākou i kēia mau ʻeke e hōʻike ana i ka hoʻololi ʻana mai kahi kaiapuni kahakai/deltaic planar i hoʻomalu ʻia e nā kaʻina fluvial a hiki i kahi kaiapuni piha piha i ka wā Castlegate.ʻOkoʻa ka mānoanoa o ke kino one (ka nui o ke kahawai) me ka manawa, me nā kahawai multilayer e hui pinepine ana i ka wā o Castlegate.E hoʻomau ka noiʻi ʻana, e hoʻomaka ana me ka hoʻopaʻa ʻana i ka ʻōnaehana o nā cores i koe a me ka hoʻopau ʻana me ke ʻano o nā papahana haumāna e pili ana i ka nānā ʻana i nā facies a me ke ʻano hoʻohālike 3D facies.
Ua manaʻo nā mea noiʻi mua i kahi hana no nā tectonics ʻelua papa ma Mars e pili ana i ka neʻe ʻana o ka hoʻololi ʻana i ka lima hema o ke awāwa ʻo Mariner.Ke hoʻohana nei i nā ʻano e like me Thermal Imaging System (THEMIS) satellite kiʻi, High Resolution Science Imaging Experiment (HiRISE), kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi kiʻi e like me Google Mars, ua ʻike mākou i nā hiʻohiʻona ākea ākea kokoke i ke awāwa ʻo Marineris..a me Tarsis Ryze.ʻOiai ʻoi aku ka lohi o ka neʻe ʻana o ka tectonic ma Mars, hiki iā mākou ke hoʻohālikelike i nā laina, nā ʻāpana, a me nā hui conjugate o Mars me nā hale like ma ka Honua e wehewehe i nā palena o ka pā.No ka laʻana, hiki i kahi pūʻulu o nā laina laina NE me ka hoʻoneʻe ʻana i ka lateral strike-slip koʻikoʻi a me nā hui e pili ana i ka hikina hikina o ka Tarshish Rise ke hoʻokomo i nā neʻe ʻana ma waena o nā papa ʻelua.Hiki i kā mākou nānā ʻana ke ʻike i ʻelua mau ʻaoʻao ʻē aʻe o nā papa i hiki i kēia māhele.Manaʻo mākou i ke kumu hoʻohālike tectonic e hōʻike ana i ka neʻe pili ʻana ma nā palena pā e hōʻike ana i kahi ʻōnaehana multi-plate ma Mars.
Ma ka hoʻohālikelike ʻana i ke aniau Köppen, ua wehewehe ʻia ke aniau maloʻo/semi-arid a i ʻole ke aniau B ma ke ʻano he aniau kahi i ʻoi aku ai ka ea ma mua o ka ua.Akā naʻe, ʻaʻole ʻo ia i hāʻawi i kahi kaʻina hana helu maʻamau.Manaʻo mākou i kahi inoa hou, hiki ke hoʻonui i ka ua (PEP), ma ke ʻano he ala kūpono no ka wehewehe ʻana i nā wahi semi-arid a humid.Ua like ka waiwai PEP me ka nui maoli o ka ua me ka evapotranspiration (POTET).Inā maikaʻi ka waiwai PEP, ʻo A, C, a i D paha ke aniau o ke kahua, akā, inā ʻino ka waiwai PEP, ʻo B ka hoʻohana ʻana i ka waiwai PEP.
Aia ka Kaiparowitz Formation, aia ma ka hema-waena o Utah, i ka mooolelo no ka Late Cretaceous floodplain i kahe mai ka La Ramedia Highlands a i ke Western Inland Waterway.Ua waiwai ka hoʻokumu ʻana i nā mōʻalihaku a loaʻa nā mea kanu mōʻalihaku, invertebrates, iʻa, amphibians, reptile a me nā mammals, a he mea hou ia i ka ʻepekema.Ua wehewehe mua ʻia ka wehewehe nui ʻana o kēia hoʻokumu ʻana ma ke ʻano he ʻauwaʻa a me ka waikahe i loko o nā waihona like ʻole a me nā loko iʻa.Hāʻawi kēia haʻawina i kahi wehewehe sedimentological kikoʻī o kahi mea kanu liʻiliʻi fossil quarry a wehewehe i nā kūlana deposition.